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ExPharm Pro: Effects of Drugs on Rabbit Eye: 2 ExPharm Pro: Bioassay of Histamine on the Ileum of Guinea Pig: 3 ExPharm Pro: Effect of Drugs on Ciliary Motility of Frog Oesophagus: 4 ExPharm Pro: Effect of Drugs on Isolated Frog Heart: 5 ExPharm Pro. Download the required product from the developer's site for free safely and easily using the official link provided by the developer of ExPharm for Windows below. We wish to warn you that since ExPharm for Windows files are downloaded from an external source, FDM Lib bears no responsibility for the safety of such downloads.
Expharm software, free download Cnet
Dear readers,
This last issue for 2020 completes my first decade as editor of ALTEX, and I would like to express my heartfelt gratitude to my colleagues, who have all been on the team from the start, for their unfailing enthusiasm and dedication, which made this such a fulfilling and successful time.
Starting off the issue, Federica Madia and colleagues provide Food for thought … by introducing different approaches aiming to use existing data to predict the results of other regulatory endpoints that would otherwise require animal testing. Their aim is to reduce redundancy and promote and expand the use of non-animal methods for regulatory purposes.
The t4 Workshop Report by Costanza Rovida and co-authors lays out the main issues that need to be addressed for the read-across approach for toxicity assessment to gain better regulatory acceptance worldwide and explains how new approach methodologies can contribute. Biokinetics, which is one of these main issues, is dealt with in more detail in a Consensus Report by Ans Punt and co-authors. Biokinetics can inform on relevant chemical concentrations and metabolites that need to be considered in in vitro tests. The article discusses how this bottleneck can be unblocked by harnessing new technologies but also by forming an OECD expert group on biokinetics to steer the process.
The monocyte activation test was developed to replace pyrogenicity testing in rabbits for parenteral products. Marilena Etna et al. have successfully optimized the test for batch release of tick-borne encephalitis virus vaccines. The assay is shown to be highly sensitive also for this product but requires an adaptation of the validity criteria.
Patients on ventilators are at risk of developing ventilator-induced lung injury (VILI) owing to mechanical stress. Harnessing their human cell model of VILI to investigate the protective effects of azithromycin, which are unrelated to its antibacterial activity, Jon Joelsson and colleagues show that the cell model can be used to elucidate the mechanistic basis of such anti-inflammatory and barrier-protective effects, supporting its relevance as a non-animal model of VILI.
When a bone is fractured, blood cells from ruptured vessels and bone marrow cells together form a fracture hematoma, within which bone healing starts. Moritz Pfeiffenberger et al. present a novel model of the human fracture hematoma, based on primary human cells cultured under hypoxic conditions, with which either drug-induced inhibition of fracture healing or the rescue of delayed fracture healing can be modeled. Thus, this human-relevant method lends itself to the replacement of animal experiments in early preclinical studies of fracture healing.
Back to back papers by Britta Wareing et al. and Andreas Natsch et al. report on the kinetic direct peptide reactivity assay (kDPRA), a modification of an OECD test guideline test, which differentiates between strong and weak skin sensitizers. The predictivity of the kDPRA is comprehensively proven based on 180 chemicals in the first paper, and its inter- and intra-laboratory reliability is successfully demonstrated in the second paper. Based on the recommendations of the independent peer review, it is expected that the kDPRA soon will be included in the OECD TG 442C so that it can replace animal tests currently performed for subclassification of skin sensitizers.
Zunwei Chen and colleagues present a high-throughput in vitro screening model to assess the toxicity of environmental chemicals based on a panel of five cell types representing liver, nervous system, heart and endothelium, and a matrix of different endpoints. They find that this model is a conservative and fast alternative to in vivo tests that can deliver essential risk information for decision-making, e.g., in response to chemical spills.
Reports of neurological symptoms in COVID-19 patients raised the question whether the virus can infect the brain. Korin Bullen and team set out to answer this question in the human induced pluripotent stem cell-derived in vitro BrainSphere model, in which they found that the ACE2 receptor is expressed. They show evidence of a productive infection with SARS-CoV-2 in a small population of neural cells, indicating that infection of the brain could endanger vulnerable patient populations.
The BenchMarks article by Jaffar Kisitu explores the difference between nominal and free concentrations of chemicals, what factors affect the free concentration, and how it can be estimated. These considerations are essential for comparison of effective concentrations in different in vitro assays or their extrapolation to other models or applications.
A letter by Katharina Hohlbaum et al. reports on a survey on the views of animal facility and scientific staff on non-aversive mouse handling after a lecture and discussion on the subject. Meeting Reports on ways to increase the availability of human tissue for research purposes, in vitro strategies for food and environmental safety, and COVID-19-related research projects as well as the Corners provide insight into recent 3R-related activities. Please note that current news and upcoming events, including many insightful webinars, are published on our website.
Finally, we wish to thank you, our authors, reviewers, subscribers, readers, members and sponsors, for your continued support of ALTEX in 2020 and hope you and your families stay safe and healthy.
Sonja von Aulock and the ALTEX Edition Editorial Office
with Franz P. Gruber and the Board of ALTEX Edition
with Franz P. Gruber and the Board of ALTEX Edition
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FUJIFILM MyFinePix Studio
FUJIFILM MyFinePix Studio is an application that you can use to manage your images and videos in a number of ways: you can easily edit and print your images and videos, as well as instantly upload them on various social networks, such as Facebook and YouTube. The interface provides access to four main sections of the program: Import Images, Print images, View images and Net Service.
- Publisher: Fujifilm Co., Ltd.
- Home page:www.fujifilm.com
- Last updated: March 25th, 2012
MiniOS7 Studio Ver
MiniOS7 Studio packs everything you need. Take advantage of the IDE, and MiniOS7 Studio will impress you so much.MiniOS7 Studio offers an Integrated Development Environment for our customers. With MiniOS7 Studio, users can solely focus on developing programs, enjoy his/her own independent projects and most importantly, get fully support from ICP DAS.
- Publisher: ICPDAS
- Home page:www.icpdas.com
- Last updated: January 21st, 2010
KEYENCE VT STUDIO Ver.3
VT STUDIO makes it simple and easy to complete the bothering works such as resize, alignment, and copy. With the VT3, name plate size can be automatically adjusted. To do this, simply select auto adjust and the text will always fits the name plate size. When you lay the components out, grid lines can be displayed both from left to right and up and down.
- Publisher: KEYENCE Corporation
- Last updated: April 27th, 2012
McAfee ePolicy Orchestrator
McAfee ePolicy Orchestrator (ePO) is an essential component of the McAfee Security Management Platform for business enterprises. It provides unified management of endpoint, network, and data security. By means of some powerful automations, it slashes incidence response times, dramatically strengthens protection and cuts down cost and complexity of managing risk and security.
- Publisher: McAfee, Inc.
- Home page:www.mcafee.com
- Last updated: July 29th, 2014
IPA Unicode (ver 1.2 US) MSK
Choose which download you wish, either the US or UK keyboard layout. Download and unzip the zip file to an easy-to-remember location on your hard drive (if you are uncertain what to do with a .zip file, see Decompression Utilities, Downloading & Installation Tips)
- Publisher: SIL International
- Home page:scripts.sil.org
- Last updated: February 29th, 2012
EEC Analyzer
The EEC Analyzer (also refered to as EA) is a tool that can analyze data produced by most of todays common data loggers. The EA can also log data and retrieve Diagnostic Trouble Codes (DTC) with the ELM320 Scan Tool or ELM327 Scan Tool. This scan tool is an OBDII interface that allows the EEC Analyzer to log and monitor live data.
- Publisher: EEC Analyzer
- Last updated: April 5th, 2010
ExPharm for Windows
ExPharm will be helpful for UGs doing a course in Pharmacology. The software can be used for Medical and Dental UGs and also for the students of paramedical courses such as nursing, pharmacy, medical laboratory technology and physiotherapy.The entire package is mouse operable and the need to use key board is minimal.
- Publisher: JIPMER
- Home page:www.indphar.org
- Last updated: May 6th, 2009
EasyOpenOffice
EasyOpenOffice is a set of classes and templates providing you an ability to use OpenOffice from your Clarion applications. EasyOpenOffice supports Clarion for Windows ver. 5.5 and 6.3/7./7.3. EasyOpenOffice Class and Templates supports 32 bit applications (Clarion and ABC template chains).
- Publisher: Ingasoftplus
- Home page:ingasoftplus.com
- Last updated: November 9th, 2011
Cheetah Sync
By installing a small free application on your computer and downloading the free Android app, you can pair a folder on your Android device with a folder on your computer. The files will then sync wirelessly to your Android device or to your computer, or both! It is all highly configurable and up to you. Sync whatever you want, no cloud needed. No storage limitations.
Expharm software, free download Windows 7
- Publisher: JRT Studio LLC
- Home page:www.jrtstudio.com
- Last updated: March 22nd, 2012
ProStudioMasters Download Manager
The ProStudioMasters Download Manager handles the sometimes intermittent nature of the internet, allowing file downloads to be paused and resumed as necessary, and it also verifies that downloaded tracks are bit-for-bit accurate before making them available for playback.
- Publisher: ProStudioMasters.com
- Home page:www.prostudiomasters.com
- Last updated: August 7th, 2015
Pirate Ship 3D Screensaver
Expharm software, free download
Pirate Ship 3D Screensaver:Just a few centuries ago the seas were ruled by bloodthirsty and greedy pirates. They not only robbed the civilian fleet but also battled each other for the stolen loot. A lot of their ships sank in the Caribbean and still remain their. In this screensaver we get an awesome opportunity to dive into the depths and take a closer look at one of these pirate ships.Features:Photo-realistic 3D graphicstView of a real submerged pirate shipNumerous mysterious creatures of the deep seaEnchanting beauty of the underwater worldFull 3D environmentRelaxing enigmatic musicFPS counterTrue spirit of the glorious history of the pirates of the Caribbean!Password protection.
- Publisher: Astrogemini
- Home page:www.astrogemini.com
- Last updated: March 7th, 2008
Star Wars 3D Screensaver
Download this 3D screensaver and turn you screen into a teleport gateway to the mysterious galaxy of star wars. You will definitely appreciate the outstanding graphics and the enchanting space scenery with fascinating special effects.
- Publisher: Astro Gemini
- Home page:www.terminalstudio.com
- Last updated: May 27th, 2020
Challenger Tetris
Do you think you can play Tetris well? Well, this game will challenge you! You will have to apply the best of your skills to be successful in this one and we are sure you will not be bored! Test yourself and find out how good you really are.
- Publisher: TERMINAL Studio
- Home page:www.x-ways.net
- Last updated: September 22nd, 2020
Space Flight 3D Screensaver
Space Flight 3D Screensaver takes you on a journey to outer space.This unique screensaver will allow you to feel and see what an astronaut feels every time he is flying out there.I cannot tell you that the scenes are totally realistic. However they are of a very good quality and with a little imagination you will feel as if you were there.
- Publisher: TERMINAL Studio
- Home page:www.terminalstudio.com
- Last updated: May 27th, 2020
Expharm software, free download Windows 10
Colibri SDK for WINCE
1. Download the Colibri SDK from Toradex (link) and save it to the desktop.2. Install Visual Studio (tested to work with 2005 & 2008) on Windows3. Run cmd.exe an an administrator4. Browse to your desktop5. Type the following 'msiexec /qb /i colibri_SDK_1_0.msi'6. Ensure the SDK has been installed by opening Visual Studio and clicking (tools -> options -> device tools -> devices).
- Publisher: Toradex
- Home page:developer.toradex.com
- Last updated: June 25th, 2010
Android Studio
Android Studio makes it easy to build applications for Android devices. Its allows you to create complex layouts with ConstraintLayout by adding constraints from each view to other views and guidelines; you can then preview your layout on various device configurations and screen resolutions.
- Publisher: Android Developers
- Home page:developer.android.com
- Last updated: November 16th, 2020
AutoPlay Media Studio
Expharm software, free download. software
AutoPlay Media Studio is a program that lets you create software applications easily and fast, even if you don't know a word of programming. It has an extensive template menu from where you can choose the type of project you need to create. The main disadvantage I found is the program's cost. This can be a limiting factor for many users.
- Publisher: Indigo Rose Software
- Home page:www.indigorose.com
- Last updated: December 25th, 2016
Samplitude Music Studio Download version
Samplitude Music Studio is a multitrack recording and editing application for all types of audio material featuring unlimited editing options. It's easy to use and follows three simple steps: Download and record, Arrange and edit, and Export and use. You can try this application for a period of 7 days expandable to 30 days.
- Publisher: MAGIX AG
- Home page:www.magix.com
- Last updated: June 7th, 2009